Positron Emission Tomography
Typically, a standardized uptake value (SUV), a quantity that incorporates the patient’s size and the injected dose, that is more than 2.0 is considered to be suggestive of malignancy, whereas lesions with SUVs less than this value are considered to be benign.
What does increased uptake mean on a PET scan?
A recent infection or injury may show up on PET. This means that when a PET Scan does not show uptake (meaning it is not hot) there is unlikely to be cancer. However, when a PET Scan detects uptake of the FDG tracer, it means that it might be cancer, but is not definite.
How do you calculate an SUV for a pet?
SUV is multiplied by plasma glucose concentration / 5.0 (where 5.0 represents the population average of plasma glucose concentration). Increased plasma glucose concentration may introduce also regional changes in FDG uptake, resembling Alzheimer disease -like patterns in the brain (Ishibashi et al., 2015).
What is SUV in lung cancer?
Integrated [18F]fluorodeoxyglucose positron emission tomography–computed tomography (PET-CT) scan is a widely used modality in the evaluation of lung cancer. Our goal was to determine the ability of the stan- dard uptake value (SUV) of the primary tumor (SUV-T) and regional lymph nodes (SUV-N) to predict survival.
Do PET scan hotspots always mean cancer?
Abnormal cells in the body that use a lot of glucose will also appear as “hot spots.” Cancer cells are highly metabolic and use a lot of sugar. PET scans do not diagnose cancer; they only show areas of abnormal uptake of the tracer material. Other diseases can produce “hot spots,” such as infection.